rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
17
|
pubmed:dateCreated |
1995-10-26
|
pubmed:abstractText |
We describe severe and unexpected multisystem toxicity that occurred during a study of the antiviral nucleoside analogue fialuridine (1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil, or FIAU) as therapy for chronic hepatitis B virus infection.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0028-4793
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
26
|
pubmed:volume |
333
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
N
|
pubmed:pagination |
1099-105
|
pubmed:dateRevised |
2010-3-24
|
pubmed:meshHeading |
pubmed-meshheading:7565947-Acidosis, Lactic,
pubmed-meshheading:7565947-Adult,
pubmed-meshheading:7565947-Alanine Transaminase,
pubmed-meshheading:7565947-Antiviral Agents,
pubmed-meshheading:7565947-Arabinofuranosyluracil,
pubmed-meshheading:7565947-Chronic Disease,
pubmed-meshheading:7565947-DNA, Mitochondrial,
pubmed-meshheading:7565947-DNA, Viral,
pubmed-meshheading:7565947-Drugs, Investigational,
pubmed-meshheading:7565947-Female,
pubmed-meshheading:7565947-Hepatitis B,
pubmed-meshheading:7565947-Humans,
pubmed-meshheading:7565947-Jaundice,
pubmed-meshheading:7565947-Liver,
pubmed-meshheading:7565947-Liver Failure,
pubmed-meshheading:7565947-Liver Transplantation,
pubmed-meshheading:7565947-Male,
pubmed-meshheading:7565947-Middle Aged,
pubmed-meshheading:7565947-Pancreatitis,
pubmed-meshheading:7565947-Peripheral Nervous System Diseases
|
pubmed:year |
1995
|
pubmed:articleTitle |
Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B.
|
pubmed:affiliation |
Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Clinical Trial, Phase II
|