Linked Life Data

7565614

Source:http://linkedlifedata.com/resource/pubmed/id/7565614

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1995-10-23
pubmed:databankReference
pubmed:abstractText
A novel gene, brd1, has been cloned from the fission yeast Schizosaccharomyces pombe. The predicted brd1 product contains two copies of an imperfect repeat of 96 amino acid residues in its N-terminal half. These each include a region with high homology to the bromodomains found in transcriptional activator proteins from a diversity of eukaryotes. An in vivo deletion of the complete brd1 open reading frame is not lethal but cells exhibit thermosensitivity, with reductions in both cell growth and stationary phase survival at 36 degrees C. brd1 maps adjacent to the gene suc1, but is expressed separately to give a low abundance 2.1 kb mRNA.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0026-8925
pubmed:author
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
248
pubmed:geneSymbol
brd1, suc1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
491-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
A fission yeast gene mapping close to suc1 encodes a protein containing two bromodomains.
pubmed:affiliation
Department of Biological Sciences, University of Exeter, Washington Singer Laboratories, U.K.
pubmed:publicationType
Journal Article