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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1995-11-7
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pubmed:abstractText |
Adult T cell leukemia (ATL) is the T cell malignancy caused by human T lymphotropic virus type I (HTLV-I), and HTLV-I is also the causative agent of HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Although HTLV-I causes both diseases, concomitant occurrence is reported to be rare. This paper describes two cases of HAM/TSP that developed into lymphoma-type ATL after the onset of HAM/TSP. In one case, the same HTLV-I infected clone could be detected by polymerase chain reaction in peripheral blood obtained when the patient was diagnosed as HAM/TSP. This finding showed that the HTLV-I clone already existed at the stage of HAM/TSP. Since frequent detection of clonal proliferation of HTLV-I infected cells has been reported previously in patients with HAM/TSP, careful follow-up is needed for patients with HAM/TSP.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0887-6924
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
9
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
N
|
pubmed:pagination |
1768-70
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7564523-Base Sequence,
pubmed-meshheading:7564523-Disease Progression,
pubmed-meshheading:7564523-Female,
pubmed-meshheading:7564523-Human T-lymphotropic virus 1,
pubmed-meshheading:7564523-Humans,
pubmed-meshheading:7564523-Leukemia, T-Cell,
pubmed-meshheading:7564523-Male,
pubmed-meshheading:7564523-Middle Aged,
pubmed-meshheading:7564523-Molecular Sequence Data,
pubmed-meshheading:7564523-Paraparesis, Tropical Spastic,
pubmed-meshheading:7564523-Polymerase Chain Reaction
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pubmed:year |
1995
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pubmed:articleTitle |
Adult T cell leukemia following HTLV-I-associated myelopathy/tropical spastic paraparesis: case reports and implication to the natural course of ATL.
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pubmed:affiliation |
Second Department of Internal Medicine, Kumamoto University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|