Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1995-10-26
pubmed:abstractText
We re-evaluated several antibiotics including newer ones, for their in vitro killing activity, as well as their inhibitory activity, against clinical isolates of periodontopathic bacteria. Tetracyclines were active against Porphyromonas gingivalis, and were highly active against Prevotella intermedia, but demonstrated only a low killing activity against Actinobacillus actinomycetemcomitans. Rokitamycin, a new macrolide, and clindamycin were highly active against P. gingivalis and P. intermedia, but showed very weak killing activity against A. actinomycetemcomitans. Quinolones demonstrated excellent bactericidal activity against A. actinomycetemcomitans, and good inhibitory and bactericidal activity against P. gingivalis and P. intermedia. Metronidazole had an activity almost equivalent to quinolones against P. gingivalis and P. intermedia; but it was the least active against A. actinomycetemcomitans.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents, http://linkedlifedata.com/resource/pubmed/chemical/Anti-Infective Agents, http://linkedlifedata.com/resource/pubmed/chemical/Antitrichomonal Agents, http://linkedlifedata.com/resource/pubmed/chemical/Clindamycin, http://linkedlifedata.com/resource/pubmed/chemical/Erythromycin, http://linkedlifedata.com/resource/pubmed/chemical/Fluoroquinolones, http://linkedlifedata.com/resource/pubmed/chemical/Metronidazole, http://linkedlifedata.com/resource/pubmed/chemical/Minocycline, http://linkedlifedata.com/resource/pubmed/chemical/Miocamycin, http://linkedlifedata.com/resource/pubmed/chemical/Naphthyridines, http://linkedlifedata.com/resource/pubmed/chemical/Ofloxacin, http://linkedlifedata.com/resource/pubmed/chemical/Quinolones, http://linkedlifedata.com/resource/pubmed/chemical/Tetracycline, http://linkedlifedata.com/resource/pubmed/chemical/rokitamycin, http://linkedlifedata.com/resource/pubmed/chemical/sparfloxacin, http://linkedlifedata.com/resource/pubmed/chemical/tosufloxacin
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0022-3484
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
290-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
In vitro activity of tetracyclines, macrolides, quinolones, clindamycin and metronidazole against periodontopathic bacteria.
pubmed:affiliation
Department of Microbiology, Hiroshima University School of Dentistry, Japan.
pubmed:publicationType
Journal Article, Comparative Study