Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1995-11-3
|
| pubmed:abstractText |
Hereditary nonpolyposis colorectal cancer (HNPCC) has been linked recently to a defect in repairing mismatched nucleotides in DNA. The aim of this study was to screen for germline mutations that result in prematurely truncated proteins in two of the mismatch repair genes identified at this time, hMLH1 and hMSH2, in a consecutive series of patients belonging to familial aggregations of colorectal cancer.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0016-5085
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
109
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
N
|
| pubmed:pagination |
1368-74
|
| pubmed:dateRevised |
2011-9-22
|
| pubmed:meshHeading |
pubmed-meshheading:7557107-Base Sequence,
pubmed-meshheading:7557107-Colorectal Neoplasms, Hereditary Nonpolyposis,
pubmed-meshheading:7557107-Genetic Testing,
pubmed-meshheading:7557107-Humans,
pubmed-meshheading:7557107-Molecular Sequence Data,
pubmed-meshheading:7557107-Mutation,
pubmed-meshheading:7557107-Polymerase Chain Reaction,
pubmed-meshheading:7557107-Protein Biosynthesis,
pubmed-meshheading:7557107-Transcription, Genetic
|
| pubmed:year |
1995
|
| pubmed:articleTitle |
In vitro transcription/translation assay for the screening of hMLH1 and hMSH2 mutations in familial colon cancer.
|
| pubmed:affiliation |
Roche Biomedical Laboratories, Research Triangle Park, North Carolina, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|