rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1995-11-2
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pubmed:abstractText |
We report on a double-blind, placebo-controlled study of carbamazepine (CBZ) treatment for cocaine dependence. A previously reported uncontrolled study found CBZ to be a beneficial pharmacotherapy for cocaine dependence. Statistical analyses were performed on data from 82 subjects who were randomized to 10 weeks' treatment with either CBZ, titrated to 4-12 micrograms/ml, (n = 37) or placebo (n = 45). The two treatment groups did not differ for primary outcome measures of retention time in treatment, urine samples positive for cocaine metabolite, subject reported desire for cocaine or for subject reported side-effects. CBZ was not an effective treatment in this study.
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pubmed:grant |
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0376-8716
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
38
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
221-7
|
pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7555622-Adult,
pubmed-meshheading:7555622-Anticonvulsants,
pubmed-meshheading:7555622-Carbamazepine,
pubmed-meshheading:7555622-Cocaine,
pubmed-meshheading:7555622-Dose-Response Relationship, Drug,
pubmed-meshheading:7555622-Double-Blind Method,
pubmed-meshheading:7555622-Drug Administration Schedule,
pubmed-meshheading:7555622-Female,
pubmed-meshheading:7555622-Humans,
pubmed-meshheading:7555622-Kindling, Neurologic,
pubmed-meshheading:7555622-Male,
pubmed-meshheading:7555622-Middle Aged,
pubmed-meshheading:7555622-Narcotics,
pubmed-meshheading:7555622-Substance Abuse Detection,
pubmed-meshheading:7555622-Substance-Related Disorders,
pubmed-meshheading:7555622-Treatment Outcome
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pubmed:year |
1995
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pubmed:articleTitle |
Carbamazepine treatment for cocaine dependence.
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pubmed:affiliation |
Department of Psychiatry, University of Pennsylvania, Philadelphia 19104, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Randomized Controlled Trial
|