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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1995-11-21
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pubmed:abstractText |
The pilocarpine iontophoresis test (P-test) is used as a predictor of the capacity to produce sweat. Therefore, we studied the reproducibility of this test in 12 normal subjects on 10 consecutive days. Furthermore, we determined whether the P-test reflects whole-body and regional sweat secretion during exercise in the heat. Finally, we determined whether the P-test stimulates the eccrine sweat glands to maximal sweat secretion. Six growth hormone-deficient (GHD) patients who are known to have decreased sweating, and 11 healthy control subjects were studied. To induce maximal sweat secretion, the patients exercised on a bicycle ergometer at a workload corresponding to 40% of their maximal aerobic power (VO2max). The 11 healthy subjects exercised at a workload of 150 W. All subjects exercised for 60 min in ambient air at 35 degrees C, with 50% relative humidity. The P-test showed a mean day-to-day variation of 20.8% between individual subjects. There was a significant positive correlation between the P-test and regional sweat secretion (r2 = 0.74). The correlation coefficient (r2) was 0.50 for the correlation between the P-test and whole-body sweat secretion, and 0.52 for the correlation between regional sweat secretion and whole-body sweat secretion. We conclude that the pilocarpine iontophoresis test reflects heat- and exercise-induced sweating capacity. However, this test does not induce maximal sweating, and it cannot be used as a single reliable predictor of whole-body sweating, due to considerable day-to-day variation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0144-5979
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
409-14
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:7554774-Adult,
pubmed-meshheading:7554774-Exercise,
pubmed-meshheading:7554774-Exercise Test,
pubmed-meshheading:7554774-Female,
pubmed-meshheading:7554774-Hot Temperature,
pubmed-meshheading:7554774-Humans,
pubmed-meshheading:7554774-Humidity,
pubmed-meshheading:7554774-Iontophoresis,
pubmed-meshheading:7554774-Male,
pubmed-meshheading:7554774-Muscarinic Agonists,
pubmed-meshheading:7554774-Oxygen Consumption,
pubmed-meshheading:7554774-Pilocarpine,
pubmed-meshheading:7554774-Sweating
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pubmed:year |
1995
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pubmed:articleTitle |
Pilocarpine iontophoresis test: an index of physiological sweat secretion?
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pubmed:affiliation |
August Krogh Institute, University of Copenhagen, Denmark.
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pubmed:publicationType |
Journal Article,
Clinical Trial
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