|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
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|
pubmed:dateCreated |
1995-11-6
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|
pubmed:abstractText |
Two infants, aged 8.5 and 11 months, were admitted for meningitis caused by Streptococcus pneumoniae. Failure of cefotaxime led to the identification of highly penicillin-G-resistant strains. Minimum inhibitory concentrations (MICs) for penicillin were > 2 micrograms/ml, and cefotaxime MICs were 2 micrograms/ml. Both patients rapidly responded to a combination of i.v. imipenem and rifampicin. It is now mandatory to test in-vitro susceptibilities of Streptococcus pneumoniae to penicillin G and other beta-lactam agents when meningitis is diagnosed in infants.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Jul
|
|
pubmed:issn |
0803-5253
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:volume |
84
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
831-3
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|
pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7549311-Anti-Bacterial Agents,
pubmed-meshheading:7549311-Cefotaxime,
pubmed-meshheading:7549311-Cephalosporins,
pubmed-meshheading:7549311-Drug Therapy, Combination,
pubmed-meshheading:7549311-Humans,
pubmed-meshheading:7549311-Imipenem,
pubmed-meshheading:7549311-Infant,
pubmed-meshheading:7549311-Male,
pubmed-meshheading:7549311-Meningitis, Pneumococcal,
pubmed-meshheading:7549311-Penicillin Resistance,
pubmed-meshheading:7549311-Rifampin,
pubmed-meshheading:7549311-Streptococcus pneumoniae,
pubmed-meshheading:7549311-Thienamycins
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|
pubmed:year |
1995
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|
pubmed:articleTitle |
Failure of cefotaxime treatment in two children with meningitis caused by highly penicillin-resistant Streptococcus pneumoniae.
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|
pubmed:affiliation |
Laboratoire de Microbiologie, Hôpital Antoine Béclère, Clamart, France.
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pubmed:publicationType |
Journal Article,
Case Reports
|
