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pubmed-article:7539109pubmed:abstractTextIntensive chemotherapy for acute myelogenous leukemia (AML) continues to yield low rates of complete remission and survival among patients over the age of 65 years. Infection-related mortality is particularly high among these patients during the period of neutropenia that follows chemotherapy. We determined the effect of lenograstim (glycosylated recombinant human granulocyte colony-stimulating factor) on mortality at eight weeks (the main end point) and the rate of complete remission among patients with AML who were 65 years old or older.lld:pubmed
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pubmed-article:7539109pubmed:articleTitleA controlled study of recombinant human granulocyte colony-stimulating factor in elderly patients after treatment for acute myelogenous leukemia. AML Cooperative Study Group.lld:pubmed
pubmed-article:7539109pubmed:affiliationHôpital Saint-Louis, Service Clinique des Maladies du Sang, Paris, France.lld:pubmed
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