Linked Life Data

753649

Source:http://linkedlifedata.com/resource/pubmed/id/753649

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1979-10-26
pubmed:abstractText
Specific cell mediated immunity to polio antigens was investigated in 22 children suffering from acute paralytic poliomyelitis by the macrophage migration inhibition (MIF) technique. A positive response was observed in 9 out of the 11 patients tested 1-14 days after the onset of the paralysis and in 6 out of the 8 patients tested between 15-90 days. In one case, the response was positive even before paralysis became evident. Out of the 8 patients tested 90-360 days after paralysis, only 3 gave positive results. No response whatsoever could, on the other hand, be observed in the great majority of children tested 1-3 months after having received oral polio vaccine or in healthy adults. These findings demonstrate that in poliomyelitis the specific C.M.I. response can be detected before the circulating antibodies and suggest that possibility of the use of this technique in the early diagnosis of poliomyelitis as well as in the differentiation between this disease and other neurological disorders.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0301-5149
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
179-82
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
The cell mediated immune response in acute poliomyelitis and its use in early diagnosis.
pubmed:publicationType
Journal Article