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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
1995-4-21
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pubmed:abstractText |
The induction of vascular cell adhesion molecule-1 (VCAM-1) and E-selectin by tumor necrosis factor-alpha (TNF) is mediated by mobilization of the transcription factor nuclear factor-kappa B (NF-kappa B). Since salicylates have been reported to inhibit NF-kappa B activation by preventing the degradation of its inhibitor I kappa B, we studied a potential inhibition of this pathway by acetylsalicylate (aspirin) in human umbilical vein endothelial cells (HUVECs).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0009-7322
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1914-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7534663-Aspirin,
pubmed-meshheading:7534663-Cell Adhesion,
pubmed-meshheading:7534663-Cell Adhesion Molecules,
pubmed-meshheading:7534663-Cells, Cultured,
pubmed-meshheading:7534663-E-Selectin,
pubmed-meshheading:7534663-Endothelium, Vascular,
pubmed-meshheading:7534663-Humans,
pubmed-meshheading:7534663-Monocytes,
pubmed-meshheading:7534663-NF-kappa B,
pubmed-meshheading:7534663-Tumor Necrosis Factor-alpha,
pubmed-meshheading:7534663-Vascular Cell Adhesion Molecule-1
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pubmed:year |
1995
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pubmed:articleTitle |
Aspirin inhibits nuclear factor-kappa B mobilization and monocyte adhesion in stimulated human endothelial cells.
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pubmed:affiliation |
Institut für Prophylaxe der Kreislaufkrankheiten, Ludwig-Maximilians-Universität, München, Germany.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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