Linked Life Data

7531382

Source:http://linkedlifedata.com/resource/pubmed/id/7531382

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1995-3-8
pubmed:abstractText
The morphological events associated with the formation of capillary sprouts were examined in the dental organs to elucidate the morphological processes of angiogenesis in epithelial tissues. Mandibular first molars of 2-day-old male rats were processed for routine observation by transmission electron microscopy. In angiogenic regions, capillaries were located in the caves delineated by outer enamel epithelium, and extravasated erythrocytes were often observed in the stellate reticulum. At the capillary sprout, endothelial cells were amoeboidal in shape, and extended their filopodia to the fluffy extracellular matrix. On the other hand, each endothelial cell interdigitated with each process to form a tubule, and bulbous cell processes filled the luminal side of capillaries. Coated vesicles or pits 50-90 nm in diameter lined the luminal plasma membrane and that comprising the base of filopodial processes. Some endothelial sprouting tips (30 of 47 sprouts) were associated with pericyte-like cells. However, pericyte-like cells were observed in most of the caves where capillaries were located or destined to be located. We investigated the dynamic status of endothelial cells via parameters such as cell elongation and spreading which were supported by the additional observation of membranous components such as coated vesicles at the capillary sprouting region. It was also suggested that pericyte-like cells participated in angiogenesis of epithelial tissues by guiding the sprouts and sealing labile junctions between endothelial cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0022-7722
pubmed:author
pubmed:issnType
Print
pubmed:volume
69
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
684-96
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Ultrastructural observation of capillary sprouts in the dental organs of rat molars.
pubmed:affiliation
Department of Oral Histology, Kanagawa Dental College, Japan.
pubmed:publicationType
Journal Article