Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1995-1-25
pubmed:abstractText
Sensorineural hearing loss in early childhood may severely interfere with normal speech and language development. This by itself requires pursuit of an effective therapeutic procedure. Here we report the results of therapy with a rheological agent and procaine-HCl with or without the addition of steroids. Immunological testing was also studied for possible circulating antibodies in sera of affected children. Retrospective analysis of therapeutic results showed that the therapeutic procedure employed may be beneficial, since hearing improved considerably in some cases. Since an autoimmune-related sensorineural hearing loss has been postulated for some years, results presented here could be used as an argument for the presence of antibody-related inner ear disorders in early childhood. These findings suggest that circulating antibodies in children suffering from sensorineural hearing losses produce an inflammatory process involving inner ear structures. Circulating antibodies may also indicate a secondary immune reaction. However, sensory hearing loss occurring in early childhood may be steroid sensitive.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0017-6192
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
636-42
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:7528187-Adolescent, pubmed-meshheading:7528187-Audiometry, pubmed-meshheading:7528187-Autoantibodies, pubmed-meshheading:7528187-Autoimmune Diseases, pubmed-meshheading:7528187-Child, pubmed-meshheading:7528187-Child, Preschool, pubmed-meshheading:7528187-Combined Modality Therapy, pubmed-meshheading:7528187-Dextrans, pubmed-meshheading:7528187-Ear, Inner, pubmed-meshheading:7528187-Female, pubmed-meshheading:7528187-Follow-Up Studies, pubmed-meshheading:7528187-Hearing Loss, Sensorineural, pubmed-meshheading:7528187-Hearing Loss, Sudden, pubmed-meshheading:7528187-Hemodilution, pubmed-meshheading:7528187-Humans, pubmed-meshheading:7528187-Infant, pubmed-meshheading:7528187-Male, pubmed-meshheading:7528187-Prednisolone, pubmed-meshheading:7528187-Procaine, pubmed-meshheading:7528187-Reflex, Acoustic
pubmed:year
1994
pubmed:articleTitle
[Drug therapy of acute inner ear hearing loss in childhood and adolescence].
pubmed:affiliation
Abteilung Phoniatrie und Pädaudiologie, HNO-Klinik, Universität Tübingen.
pubmed:publicationType
Journal Article, English Abstract