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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
23
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pubmed:dateCreated |
1994-12-16
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pubmed:abstractText |
Cellular proliferation, as measured by S-phase fraction, is an important predictor of breast cancer prognosis. The insulin-like growth factors (IGFs) have been shown to regulate proliferation in both normal and neoplastic cells by interacting with specific cell surface receptors. In addition to these receptors, high-affinity extracellular binding proteins also modulate IGF action. These insulin-like growth factor-binding proteins (IGFBPs) could influence breast cancer growth and, like other biological parameters of proliferation, could be related to prognosis.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
pubmed:issn |
0027-8874
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
7
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pubmed:volume |
86
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1785-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7525978-Breast Neoplasms,
pubmed-meshheading:7525978-Carrier Proteins,
pubmed-meshheading:7525978-Disease-Free Survival,
pubmed-meshheading:7525978-Gene Expression,
pubmed-meshheading:7525978-Humans,
pubmed-meshheading:7525978-Insulin-Like Growth Factor Binding Proteins,
pubmed-meshheading:7525978-Prognosis
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pubmed:year |
1994
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pubmed:articleTitle |
Prognostic significance of insulin-like growth factor-binding protein expression in axillary lymph node-negative breast cancer.
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pubmed:affiliation |
Department of Medicine, University of Texas Health Science Center at San Antonio 78284-7884.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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