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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1994-12-9
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pubmed:abstractText |
Aprotinin has recently been shown to reduce postoperative bleeding and transfusion requirements associated with coronary artery bypass grafting. One concern with its use, however, is that it may have a deleterious effect on graft patency because it promotes hemostasis. Forty-seven patients undergoing coronary artery bypass. Forty-seven patients undergoing coronary artery bypass grafting were enrolled in a prospective, randomized double-blind trial of aprotinin to determine the effect of this agent on postoperative bleeding, transfusion requirements, renal function, and graft patency. The study group was comprised of the 32 patients who underwent technically adequate ultrafast CT scans 6 to 8 weeks postoperatively to determine graft patency. Sixteen patients received aprotinin (aprotinin group) and 16 received placebo (control group).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0012-3692
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
106
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1370-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7525162-Aged,
pubmed-meshheading:7525162-Aprotinin,
pubmed-meshheading:7525162-Blood Transfusion,
pubmed-meshheading:7525162-Chi-Square Distribution,
pubmed-meshheading:7525162-Coronary Artery Bypass,
pubmed-meshheading:7525162-Coronary Vessels,
pubmed-meshheading:7525162-Double-Blind Method,
pubmed-meshheading:7525162-Follow-Up Studies,
pubmed-meshheading:7525162-Hemorrhage,
pubmed-meshheading:7525162-Humans,
pubmed-meshheading:7525162-Logistic Models,
pubmed-meshheading:7525162-Middle Aged,
pubmed-meshheading:7525162-Postoperative Care,
pubmed-meshheading:7525162-Postoperative Complications,
pubmed-meshheading:7525162-Prospective Studies,
pubmed-meshheading:7525162-Vascular Patency
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pubmed:year |
1994
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pubmed:articleTitle |
The impact of aprotinin on coronary artery bypass graft patency.
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pubmed:affiliation |
Department of Surgery, Deborah Heart and Lung Center, Browns Mills, NJ 08015-1799.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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