Linked Life Data

7524512

Source:http://linkedlifedata.com/resource/pubmed/id/7524512

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1994-12-2
pubmed:abstractText
To evaluate alpha-fetoprotein (AFP) levels in women during pregnancy and in the neonate, 256 singleton pregnancies without medical, gynecologic, obstetric, or neonatal complications were studied. Sera for measuring maternal AFP (MAFP) levels were taken in midtrimester (16 to 18 weeks), third trimester (32 to 34 weeks), and during intrapartum (38 to 41 weeks). For measuring umbilical arterial AFP (UAAFP) and umbilical venous AFP (UVAFP) levels, sera of newborn were taken from the umbilical cord at delivery. AFP levels were measured by radioimmunoassay. Our results show that the MAFP levels at third trimester were higher than during intrapartum or midtrimester. Birthweights correlated well with MAFP levels in midtrimester. However, they did not significantly correlate with the MAFP levels at third trimester or intrapartum, nor with UAAFP or UVAFP levels. UAAFP levels were not significantly different from UVAFP levels. Intrapartum MAFP correlated well with UAAFP but not with UVAFP, birthweight, or parity. The concentration gradient between fetal and maternal serum during intrapartum is approximately 750:1. We conclude that MAFP levels in midtrimester can reflect birthweight. The data of normal AFP gradient may also be useful for diagnosing intrapartum fetomaternal hemorrhage.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0735-1631
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
279-81
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Alpha-fetoprotein in women during pregnancy and in the neonate during intrapartum.
pubmed:affiliation
Department of Obstetrics and Gynecology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't