|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0005740,
umls-concept:C0008838,
umls-concept:C0016360,
umls-concept:C0025677,
umls-concept:C0034656,
umls-concept:C0034897,
umls-concept:C0042679,
umls-concept:C0078397,
umls-concept:C0278996,
umls-concept:C0282461,
umls-concept:C0334246,
umls-concept:C0460004,
umls-concept:C1516985,
umls-concept:C1521808,
umls-concept:C1707455
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
1994-11-22
|
|
pubmed:abstractText |
The EORTC Head and Neck Cancer Cooperative Group conducted a randomized comparison of cisplatin, methotrexate, bleomycin and vincristine (CABO) versus cisplatin and 5-fluorouracil (CF) versus cisplatin (C) in chemotherapy naive patients with recurrent or metastatic squamous cell carcinoma of the head and neck. The primary objectives of this study were to investigate whether the CF regimen was in anyway superior to the CABO regimen and to detect any superiority of these two combinations over cisplatin alone.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0923-7534
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
5
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
N
|
|
pubmed:pagination |
521-6
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:7522527-Adult,
pubmed-meshheading:7522527-Aged,
pubmed-meshheading:7522527-Analysis of Variance,
pubmed-meshheading:7522527-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:7522527-Bleomycin,
pubmed-meshheading:7522527-Carcinoma, Squamous Cell,
pubmed-meshheading:7522527-Chi-Square Distribution,
pubmed-meshheading:7522527-Cisplatin,
pubmed-meshheading:7522527-Disease-Free Survival,
pubmed-meshheading:7522527-Europe,
pubmed-meshheading:7522527-Female,
pubmed-meshheading:7522527-Fluorouracil,
pubmed-meshheading:7522527-Head and Neck Neoplasms,
pubmed-meshheading:7522527-Humans,
pubmed-meshheading:7522527-Male,
pubmed-meshheading:7522527-Methotrexate,
pubmed-meshheading:7522527-Middle Aged,
pubmed-meshheading:7522527-Multivariate Analysis,
pubmed-meshheading:7522527-Neoplasm Metastasis,
pubmed-meshheading:7522527-Neoplasm Recurrence, Local,
pubmed-meshheading:7522527-Prognosis,
pubmed-meshheading:7522527-Proportional Hazards Models,
pubmed-meshheading:7522527-Remission Induction,
pubmed-meshheading:7522527-Vincristine
|
|
pubmed:year |
1994
|
|
pubmed:articleTitle |
Randomized comparison of cisplatin, methotrexate, bleomycin and vincristine (CABO) versus cisplatin and 5-fluorouracil (CF) versus cisplatin (C) in recurrent or metastatic squamous cell carcinoma of the head and neck. A phase III study of the EORTC Head and Neck Cancer Cooperative Group.
|
|
pubmed:affiliation |
Centre Léon Bérard, Lyon, France.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Multicenter Study,
Clinical Trial, Phase III
|
