Linked Life Data

7522064

Source:http://linkedlifedata.com/resource/pubmed/id/7522064

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1994-10-19
pubmed:abstractText
The aim of hemodilution therapy in branch retinal vein occlusion is to lower the hematocrit (HCT) and plasma viscosity and thus to ameliorate perfusion of the affected areas. In this study we compared the influence of hemodilution therapy on the retinal hemodynamics of affected areas with unaffected areas. Thirty patients with branch vein occlusion (duration of symptoms less than 14 days) aged 40-84 years (mean 63 +/- 11 years) were examined. All patients received iso- (HCT > or = 42%) or hypervolemic (HCT < 42%) hemodilution with hydroxyethyl-starch (MW 200,000/0.5 10%, HAES-steril) for 10 days. Retinal hemodynamics were quantified by means of video fluorescein angiography assessing arteriovenous passage time (AVP) of the affected and unaffected branches. Hemodilution resulted in a significant decrease in hematocrit, plasma viscosity and erythrocyte aggregation. The arteriovenous passage time of the affected area improved significantly (before therapy 4.91 +/- 2.2 s, after therapy 3.9 +/- 1.6 s). The unaffected branch showed no significant change in the arteriovenous passage time (1.85 +/- 0.7 s before and 1.79 +/- 0.7 s after therapy). The decrease in AVP in the affected branch indicates ameliorated perfusion in the affected branch area without changing the retinal hemodynamics in unaffected areas.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0941-293X
pubmed:author
pubmed:issnType
Print
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
288-92
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
[Effect of hemodilution on retinal hemodynamics in retinal branch vein occlusion].
pubmed:affiliation
Augenklinik der RWTH Aachen.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't