Linked Life Data

7521983

Source:http://linkedlifedata.com/resource/pubmed/id/7521983

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1994-10-11
pubmed:abstractText
Pepsinogen and HCl secretion in the amphibian stomach is performed by a single cell type, the oxyntopeptic cell. The distribution of pepsinogen in gastric mucosa of Bufo marinus is heterogeneous and higher concentrations are located in the fundus. Both secretions respond to the same secretagogues. Histamine induces the highest response for the two secretions. Carbachol alone, without the endogenous histamine component, has a small effect. Forskolin and 8Br-cAMP have a similar effect to histamine. The Ca2+ ionophore, A23187, and the diacylglycerol analogue, octanoylacylglycerol (OAG) have a small effect on both secretions as carbachol. Joint addition of histamine and carbachol, or forskolin and carbachol, or of OAG and 8Br-cAMP induce a potentiated response for the two secretions. Quantitative analysis of responses and study of the relationship between them during stimulation with histamine plus carbachol revealed a non parallel and uncoupled pattern of stimulation for acid and pepsinogen secretions.
pubmed:language
spa
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5504
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
89-94
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
[Comparison of acid and pepsinogen secretion control by oxyntopeptic cell of amphibians].
pubmed:affiliation
Laboratorio de Fisiología Gastrointestinal, Instituto Venezolano de Investigaciones Científicas (I.V.I.C.), Caracas.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract, Research Support, Non-U.S. Gov't