Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1994-10-6
pubmed:abstractText
The aim of this research was to evaluate the effect of high aprotinin doses on activated coagulation time (ACT) in patients with aortocoronary bypass. A total of 100 patients were examined. All of them were administered in a double blind test either aprotinin or placebo in standard doses. Our results permit a conclusion that adequate heparinization during aprotinin therapy can be achieved at ACT values more than 750 sec and protamine sulphate dose should be estimated from initially administered heparin dose. With ACT values exceeding twofold the usual ones there was no evidence of excessive heparinization leading to marked thrombocytopenia and bleeding.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0201-7563
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
32-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Evaluation of adequate heparinization during artificial circulation in the framework of prolonged intraoperative administration of high doses of aprotinin].
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, English Abstract, Controlled Clinical Trial