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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1994-9-9
|
| pubmed:abstractText |
We describe a patient who presented with graft failure following autologous BMT, with an initial response of the neutrophil count to rHuGM-CSF but eventual loss of this response. Subsequently, this patient responded to rHuG-CSF. This could be explained by the fact that rHuG-CSF stimulates both early and late myeloid progenitor cells whereas rHuGM-CSF stimulates mainly the intermediate myeloid progenitor cells. This finding suggests that rHuG-CSF should be investigated for the treatment of patients with graft failure following ABMT.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0268-3369
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
13
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
661-3
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:7519939-Adolescent,
pubmed-meshheading:7519939-Bone Marrow Transplantation,
pubmed-meshheading:7519939-Granulocyte Colony-Stimulating Factor,
pubmed-meshheading:7519939-Granulocyte-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:7519939-Humans,
pubmed-meshheading:7519939-Male,
pubmed-meshheading:7519939-Neutropenia,
pubmed-meshheading:7519939-Recombinant Proteins,
pubmed-meshheading:7519939-Transplantation, Autologous
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Correction of neutropenia with rHuG-CSF after loss of response to rHuGM-CSF following autologous bone marrow transplant.
|
| pubmed:affiliation |
Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York 10021.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports,
Research Support, Non-U.S. Gov't
|