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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1994-9-8
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pubmed:abstractText |
Sera from 80 Malaysians with confirmed hepatocellular carcinoma were tested for five markers of the hepatitis B virus, anti-HCV and anti-HDV by enzyme immunoassay, and alpha fetoprotein (AFP) was measured by radioimmunoassay. Of the patients, 98.8% had evidence of HBV infection and 75% were positive for HBsAg--which latter correlated with AFP raised above cut-off values of 500 ng/ml (P = 0.0001) and 200 ng/ml (P = 0.005). Males correlated significantly with the presence of HBsAg (P = 0.002). Thirty-one per cent of HBsAg positive patients were also positive for HBeAg and 74% for anti-HBe. Twenty per cent of the cases were concurrently positive for both HBsAg and anti-HBs. Six of 70 (8.6%) patients were positive for anti-HCV, of whom four were also positive for HBsAg. None of 67 patients tested for anti-HDV were positive. The results strongly indicate an important aetiological role for hepatitis B virus in causation of hepatocellular carcinoma among Malaysians.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0967-4845
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
51
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
177-80
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pubmed:dateRevised |
2006-4-13
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pubmed:meshHeading |
pubmed-meshheading:7519505-Adolescent,
pubmed-meshheading:7519505-Adult,
pubmed-meshheading:7519505-Aged,
pubmed-meshheading:7519505-Aged, 80 and over,
pubmed-meshheading:7519505-Biological Markers,
pubmed-meshheading:7519505-Carcinoma, Hepatocellular,
pubmed-meshheading:7519505-Child,
pubmed-meshheading:7519505-Female,
pubmed-meshheading:7519505-Hepacivirus,
pubmed-meshheading:7519505-Hepatitis Antibodies,
pubmed-meshheading:7519505-Hepatitis B,
pubmed-meshheading:7519505-Hepatitis B Antigens,
pubmed-meshheading:7519505-Hepatitis Delta Virus,
pubmed-meshheading:7519505-Humans,
pubmed-meshheading:7519505-Liver Neoplasms,
pubmed-meshheading:7519505-Male,
pubmed-meshheading:7519505-Middle Aged,
pubmed-meshheading:7519505-alpha-Fetoproteins
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pubmed:year |
1994
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pubmed:articleTitle |
Hepatitis markers in Malaysians with hepatocellular carcinoma.
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pubmed:affiliation |
Division of Radiochemistry, Institute for Medical Research, Jalan Pahang, Kuala Lumpur, Malaysia.
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pubmed:publicationType |
Journal Article
|