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pubmed-article:7519274pubmed:abstractTextWe have isolated and characterized a rat delta-opioid receptor. The deduced amino acid sequence (372 aa) closely resembles the murine delta-opioid receptor, DOR-1. In fact, 97% of the amino acid residues are conserved between the two species, while 93% of the nucleic acid residues are identical. A 6 kb mRNA was detected in rat cortex using rat DOR-1 as a probe. When expressed in COS cells, the clone shows high-affinity opioid binding with selectivity for delta-opioids. The rat delta-opioid receptor cDNA clone will be a useful tool for studying the function of delta-opioid receptor in rats.lld:pubmed
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pubmed-article:7519274pubmed:articleTitleMolecular cloning and expression of a delta-opioid receptor from rat brain.lld:pubmed
pubmed-article:7519274pubmed:affiliationDepartment of Pharmacology and Toxicology, Medical College of Virginia, Richmond.lld:pubmed
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pubmed-article:7519274pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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