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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1994-8-24
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pubmed:abstractText |
Population studies were carried out on Caucasians from north-west Germany using the short tandem repeat (STR) systems HumVWA (locus: 12p12-12pter), HumMBP (locus: 18q23-pter) and HumFABP (locus: 4q28-q31). After electrophoresis 9 alleles could be identified for HumVWA in a sample size of 321 unrelated individuals and 4 alleles were found for HumFABP in 106 individuals. For HumMBP-A 10 alleles and for HumMBP-B 7 alleles and 1 intermediate allele were determined in a sample size of 143 individuals. No deviations from Hardy-Weinberg equilibrium could be observed. In a small family study (HumVWA-n = 129; HumMBP-n = 59; HumFABP-n = 48) no new mutations could be found for HumMBP-A and HumFABP whereas 2 mutations were found in HumMBP-B and one mutation in HumVWA. Positive results could be obtained from 1 ng-20 pg (HumVWA, HumFABP) and 1 ng-100 pg (HumMBP) template DNA.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0937-9827
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
106
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
183-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7518688-Alleles,
pubmed-meshheading:7518688-Blood Stains,
pubmed-meshheading:7518688-Carrier Proteins,
pubmed-meshheading:7518688-Chromosome Mapping,
pubmed-meshheading:7518688-DNA Mutational Analysis,
pubmed-meshheading:7518688-Fatty Acid-Binding Proteins,
pubmed-meshheading:7518688-Gene Frequency,
pubmed-meshheading:7518688-Genetics, Population,
pubmed-meshheading:7518688-Germany,
pubmed-meshheading:7518688-Humans,
pubmed-meshheading:7518688-Myelin Basic Proteins,
pubmed-meshheading:7518688-Neoplasm Proteins,
pubmed-meshheading:7518688-Phenotype,
pubmed-meshheading:7518688-Polymerase Chain Reaction,
pubmed-meshheading:7518688-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:7518688-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:7518688-Tumor Suppressor Proteins,
pubmed-meshheading:7518688-von Willebrand Factor
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pubmed:year |
1994
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pubmed:articleTitle |
Population data and forensic efficiency values for the STR systems HumVWA, HumMBP and HumFABP.
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pubmed:affiliation |
Institut für Rechtsmedizin, Münster, Germany.
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pubmed:publicationType |
Journal Article
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