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pubmed-article:7518482pubmed:abstractTextLeucine enkephalin (Leu-enk) was coupled to both T and B cell antibodies in order to investigate the possibility of enhanced immunogenicity via targeted immunization. The two antibodies used were Hm x Mo CD3 and Gt x Mo Ig, respectively. The data indicate that while both antibody carriers enhanced the immunogenicity of Leu-enk, the use of the Hm x Mo CD3 antibody resulted in a greater number of mice with positive Leu-enk specific serum titers. 12 Leu-enk cell lines were produced and one, LE4H8, was chosen for characterization.lld:pubmed
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pubmed-article:7518482pubmed:articleTitleEnhanced immunogenicity of leucine enkephalin following coupling to anti-immunoglobulin and anti-CD3 antibodies.lld:pubmed
pubmed-article:7518482pubmed:affiliationDepartment of Chemistry, University of Kansas, Lawrence 66045.lld:pubmed
pubmed-article:7518482pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:7518482pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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