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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1979-8-16
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pubmed:abstractText |
Application of synthetic human calcitonin analogue ([Asul,7]-hCT) was attempted, since it is chemically more stable than native hCT. [Asu1, 7]-hCT was successfully labeled with 125I to a specific activity ranging from 410 to 540 microCi/microgram. Sensitivity, recovery and reproducibility of the assay system using 125I-labeled [Asu1,7]-hCT analogue, standard synthetic hCT and its antibodies, were 49 pg/ml, 99.8 +/- 4%, and 7.95% (C. V. within assay) or 21.9% (C. V. between assays), respectively. The dilution curve of the sera obtained from patients with medullary carcinoma paralled well with the standard curve. 125-I-labeled [Asu1, 7]-hCT analogue can be used for routine radioimmunoassay of hCT.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0013-7219
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
617-22
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:751807-Animals,
pubmed-meshheading:751807-Calcitonin,
pubmed-meshheading:751807-Female,
pubmed-meshheading:751807-Hormones,
pubmed-meshheading:751807-Humans,
pubmed-meshheading:751807-Immune Sera,
pubmed-meshheading:751807-Iodine Radioisotopes,
pubmed-meshheading:751807-Rabbits,
pubmed-meshheading:751807-Radioimmunoassay
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pubmed:year |
1978
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pubmed:articleTitle |
Radioimmunoassay of human calcitonin using labeled [Asu1, 7]-human calcitonin analogue.
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pubmed:publicationType |
Journal Article
|