|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
1994-7-19
|
|
pubmed:abstractText |
Hailey-Hailey (Familial Benign Chronic Pemphigus) Disease is a rare autosomal dominant disorder characterized by blisters caused by suprabasal epidermal acantholysis. Another autosomal dominant skin disease, Darier's disease, has clinical and histologic features which overlap those of Hailey-Hailey disease and recently has been mapped to chromosome 12q23-q24.1. We have used linkage analysis to test whether or not a mutation in this region might also underlie Hailey-Hailey disease. This analysis, using polymorphic loci tightly linked to Darier's disease, excluded this region as the site for the disease-causing mutation in two kindreds affected with Hailey-Hailey disease.
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD44,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Cytoskeletal Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Desmoplakins,
http://linkedlifedata.com/resource/pubmed/chemical/Keratins,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Lymphocyte Homing,
http://linkedlifedata.com/resource/pubmed/chemical/loricrin
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0022-202X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
102
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
992-3
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:7516400-Adolescent,
pubmed-meshheading:7516400-Adult,
pubmed-meshheading:7516400-Alleles,
pubmed-meshheading:7516400-Antigens, CD44,
pubmed-meshheading:7516400-Carrier Proteins,
pubmed-meshheading:7516400-Chromosome Mapping,
pubmed-meshheading:7516400-Chromosomes, Human, Pair 12,
pubmed-meshheading:7516400-Cytoskeletal Proteins,
pubmed-meshheading:7516400-Darier Disease,
pubmed-meshheading:7516400-Desmoplakins,
pubmed-meshheading:7516400-Family Health,
pubmed-meshheading:7516400-Female,
pubmed-meshheading:7516400-Genetic Linkage,
pubmed-meshheading:7516400-Genotype,
pubmed-meshheading:7516400-Humans,
pubmed-meshheading:7516400-Keratins,
pubmed-meshheading:7516400-Male,
pubmed-meshheading:7516400-Membrane Proteins,
pubmed-meshheading:7516400-Middle Aged,
pubmed-meshheading:7516400-Mutation,
pubmed-meshheading:7516400-Pedigree,
pubmed-meshheading:7516400-Pemphigus, Benign Familial,
pubmed-meshheading:7516400-Receptors, Cell Surface,
pubmed-meshheading:7516400-Receptors, Lymphocyte Homing
|
|
pubmed:year |
1994
|
|
pubmed:articleTitle |
Hailey-Hailey disease is not allelic to Darier's disease.
|
|
pubmed:affiliation |
Department of Dermatology, Stanford University School of Medicine, California.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
