Linked Life Data

7514920

Source:http://linkedlifedata.com/resource/pubmed/id/7514920

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1994-6-27
pubmed:abstractText
Colourimetric assays which rely on the conversion of metabolic dyes are becoming increasingly used for measuring cell proliferation and cytotoxicity. We developed a method for measuring cellular responsiveness to interferons based on the property of interferons to induce cell defenses to virus-mediated killing. The assay has several advantages over previous assays for measuring anti-viral activity and efficiently detected cytoprotective responses to human interferon of five human melanoma cell lines infected with Semliki Forest virus. The melanoma cell lines showed a varying cytoprotective response to interferons alpha 2, alpha 4, beta and gamma, in agreement with the results of previous assays for measuring melanoma cell responsiveness to interferons based upon the inhibition of cell growth (1).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1039-9712
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1111-20
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
A colourimetric dye assay to detect anti-viral activity of interferons: sensitivity for measuring cellular responsiveness to interferons.
pubmed:affiliation
Centre for Molecular Biology and Medicine, Monash University, Clayton, Victoria, Australia.
pubmed:publicationType
Journal Article, Comparative Study