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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1994-6-14
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pubmed:abstractText |
The endothelium synthesizes and releases a relaxing factor with the physiochemical properties of nitric oxide (NO). However, the role of endothelium-derived NO in the basal regulation of systemic and pulmonary vascular resistance in humans is not known. Our primary objectives were to determine the effects of inhibiting NO synthesis on blood pressure and systemic vascular resistance and to establish the role of endothelium-derived NO in the regulation of normoxic pulmonary vascular tone.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0009-7322
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2035-40
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7514109-Adult,
pubmed-meshheading:7514109-Amino Acid Oxidoreductases,
pubmed-meshheading:7514109-Arginine,
pubmed-meshheading:7514109-Blood Pressure,
pubmed-meshheading:7514109-Cardiac Output,
pubmed-meshheading:7514109-Female,
pubmed-meshheading:7514109-Humans,
pubmed-meshheading:7514109-Male,
pubmed-meshheading:7514109-Nitric Oxide,
pubmed-meshheading:7514109-Nitric Oxide Synthase,
pubmed-meshheading:7514109-Phenylephrine,
pubmed-meshheading:7514109-Pulmonary Artery,
pubmed-meshheading:7514109-Pulmonary Circulation,
pubmed-meshheading:7514109-Pulmonary Wedge Pressure,
pubmed-meshheading:7514109-Vascular Resistance,
pubmed-meshheading:7514109-omega-N-Methylarginine
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pubmed:year |
1994
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pubmed:articleTitle |
Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans.
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pubmed:affiliation |
Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass 02115.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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