Linked Life Data

7514084

Source:http://linkedlifedata.com/resource/pubmed/id/7514084

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1994-6-16
pubmed:abstractText
The projection from the cortex to the substantia nigra (SN) in the rat was studied using the biotinylated dextran amine (BDA) anterograde tracing method. Injections of BDA into the prefrontal cortex consistently yielded labeling of the thin nerve fibers with small boutons in the SN pars compacta (SNc) and the pars reticulata (SNr). The cortico-nigral projection had a loose medio-lateral and rostro-caudal arrangement. Injections of BDA into the precentral lateral, the parietal, the temporal, and the occipital cortices resulted in sparse or no labeling of boutons in the SN. The density of boutons in the most heavily labeled region of the SN was 0.23/10(3) micron3. For comparison, similar measurement was performed in the cortico-striatal projection. The density of the boutons in the the neostriatum was 4.9/10(3) micron3. This study indicates that the entire prefrontal cortex projects to the SNc and SNr and that the terminal density of this projection is much less than the cortico-striatal projection.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
21
pubmed:volume
637
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
317-22
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
The cortico-nigral projection in the rat: an anterograde tracing study with biotinylated dextran amine.
pubmed:affiliation
University of Tennessee Memphis, College of Medicine, Department of Anatomy and Neurobiology 38163.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't