Linked Life Data

7512244

Source:http://linkedlifedata.com/resource/pubmed/id/7512244

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1994-5-9
pubmed:abstractText
The neuropeptide galanin is present in limbic brain areas important for emotionality. We examined whether central galanin may be involved in mechanisms of anxiety. Rats were tested in a pharmacologically validated animal model of anxiety, the Vogel punished drinking test. A 100% increase of punished responding was seen after 3 nmol galanin i.c.v. After 15 nmol, signs of sedation were seen, and no increase of punished responding could be observed. Drinking motivation, shock thresholds and exploratory locomotor activity were not affected by 3 nmol galanin. These results support a specific anxiolytic-like action of galanin, similar to that of the functionally related peptide, neuropeptide Y.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
24
pubmed:volume
164
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
17-20
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Anxiolytic-like action of centrally administered galanin.
pubmed:affiliation
Department of Pharmacology, University of Göteborg, Sweden.
pubmed:publicationType
Journal Article