| pubmed-article:7512027 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7512027 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:7512027 | lifeskim:mentions | umls-concept:C0085295 | lld:lifeskim |
| pubmed-article:7512027 | lifeskim:mentions | umls-concept:C0026473 | lld:lifeskim |
| pubmed-article:7512027 | lifeskim:mentions | umls-concept:C0063695 | lld:lifeskim |
| pubmed-article:7512027 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:7512027 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:7512027 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:7512027 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:7512027 | pubmed:dateCreated | 1994-5-9 | lld:pubmed |
| pubmed-article:7512027 | pubmed:abstractText | There is evidence that interleukin -10(IL-10) interferes with the costimulatory properties of antigen-presenting cells and, thereby, inhibits their ability to induce T cell activation. To determine whether this effect might involve modulation of the expression of accessory molecules, we analyzed by flow cytometry the influence of human IL-10 on the basal expression of intercellular adhesion molecule 1 (ICAM-1) as well as on the interferon gamma (IFN-gamma)-induced up-regulation of ICAM-1 and B7 at the surface of human monocytes. IL-10 inhibited both the basal expression and the IFN-gamma-induced ICAM-1 up-regulation. IL-10 also reduced B7 up-regulation on IFN-gamma-stimulated monocytes. The inhibitory effect of IL-10 both on ICAM-1 and B7 expression was shown to be dose dependent. We conclude that the ability of IL-10 to decrease both ICAM-1 and B7 expression on monocytes might contribute to its immunosuppressive properties. | lld:pubmed |
| pubmed-article:7512027 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7512027 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7512027 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:7512027 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7512027 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:7512027 | pubmed:issn | 0014-2980 | lld:pubmed |
| pubmed-article:7512027 | pubmed:author | pubmed-author:GoldmanMM | lld:pubmed |
| pubmed-article:7512027 | pubmed:author | pubmed-author:ESODAE C JEC | lld:pubmed |
| pubmed-article:7512027 | pubmed:author | pubmed-author:de BoerMM | lld:pubmed |
| pubmed-article:7512027 | pubmed:author | pubmed-author:DelvilleJ PJP | lld:pubmed |
| pubmed-article:7512027 | pubmed:author | pubmed-author:MarchantAA | lld:pubmed |
| pubmed-article:7512027 | pubmed:author | pubmed-author:GérardCC | lld:pubmed |
| pubmed-article:7512027 | pubmed:author | pubmed-author:DelvauxAA | lld:pubmed |
| pubmed-article:7512027 | pubmed:author | pubmed-author:WillemsFF | lld:pubmed |
| pubmed-article:7512027 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7512027 | pubmed:volume | 24 | lld:pubmed |
| pubmed-article:7512027 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7512027 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7512027 | pubmed:pagination | 1007-9 | lld:pubmed |
| pubmed-article:7512027 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:7512027 | pubmed:meshHeading | pubmed-meshheading:7512027-... | lld:pubmed |
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| pubmed-article:7512027 | pubmed:meshHeading | pubmed-meshheading:7512027-... | lld:pubmed |
| pubmed-article:7512027 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:7512027 | pubmed:articleTitle | Interleukin-10 inhibits B7 and intercellular adhesion molecule-1 expression on human monocytes. | lld:pubmed |
| pubmed-article:7512027 | pubmed:affiliation | Department of Immunology, Hôpital Erasme, Université Libre de Bruxelles, Belgium. | lld:pubmed |
| pubmed-article:7512027 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7512027 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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