Linked Life Data

7510628

Source:http://linkedlifedata.com/resource/pubmed/id/7510628

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1994-4-19
pubmed:abstractText
Cortical positivity as measured by slow event-related potentials is assumed to represent a decreased excitability of cortical networks and suppression of their behavioral-cognitive output. The blink reflex probe is a commonly used defensive electromyographic response whose amplitude was shown to be modulated by emotional and attentional orientation. It was used here as an indicator of cortico-subcortical excitation. In study 1, 33 healthy subjects took part in a continuous performance test (CPT). Event-related potentials were recorded from 15 standard scalp locations. Acoustic startling noise bursts were delivered during conditions that required either performance of prepared motor responses (Go), inhibition of prepared motor responses (NoGo), or had no motor significance (Irrelevant condition). During the NoGo condition, EEG surface potentials showed a widespread P300-like positivity with a central maximum. Startle responses were inhibited during the NoGo condition as compared to the Irrelevant condition. In study 2 (21 subjects) the same format was used, except that the startle reflex was elicited visually. Startle reflexes again showed smaller magnitude during the NoGo condition, which evoked larger positivity at central sites in comparison to the Irrelevant condition. The relationship between positivity in the EEG and inhibited startle responses is in line with the hypothesis that positive EEG shifts reflect a state of cortical disfacilitation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0013-4694
pubmed:author
pubmed:issnType
Print
pubmed:volume
90
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
135-44
pubmed:dateRevised
2008-9-9
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Positive shifts of event-related potentials: a state of cortical disfacilitation as reflected by the startle reflex probe.
pubmed:affiliation
Department of Medical Psychology and Behavioral Neurobiology, Eberhard-Karls-Universität, Tübingen, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't