Linked Life Data

7510555

Source:http://linkedlifedata.com/resource/pubmed/id/7510555

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-4-19
pubmed:abstractText
A set of three 3D (1H,13C,15N) triple-resonance correlation experiments has been designed to provide H1'-H8 intraresidue sugar-to-base correlations in purines in an unambiguous and efficient manner. Together, the HsCsNb, HsCs(N)bCb, and HbNbCb experiments correlate the H1' sugar proton to the H8 proton of the attached base by means of the (H1', C1', N9, C8, H8) heteronuclear scalar coupling network. The assignment strategy presented here allows for unambiguous H1'-H8 intraresidue correlations, provided that no two purines have both the same H1' and C1' chemical shifts and the same C8 and N9 chemical shifts. These experiments have yielded H1'-H8 intraresidue sugar-to-base correlations for all five guanosines in the [13C,15N] isotopically labeled RNA duplex r(GGCGCUUGCGUC)2.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0925-2738
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
129-33
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Unambiguous through-bond sugar-to-base correlations for purines in 13C,15N-labeled nucleic acids: the HsCsNb,HsCs(N)bCb, and HbNbCb experiments.
pubmed:affiliation
Pharmaceutical Research Institute, Bristol-Myers Squibb, Princeton, NJ 084543-4000.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't