| pubmed-article:7510257 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7510257 | lifeskim:mentions | umls-concept:C0013936 | lld:lifeskim |
| pubmed-article:7510257 | lifeskim:mentions | umls-concept:C0007586 | lld:lifeskim |
| pubmed-article:7510257 | lifeskim:mentions | umls-concept:C1521991 | lld:lifeskim |
| pubmed-article:7510257 | lifeskim:mentions | umls-concept:C0013138 | lld:lifeskim |
| pubmed-article:7510257 | lifeskim:mentions | umls-concept:C1306673 | lld:lifeskim |
| pubmed-article:7510257 | lifeskim:mentions | umls-concept:C0449243 | lld:lifeskim |
| pubmed-article:7510257 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:7510257 | lifeskim:mentions | umls-concept:C0441712 | lld:lifeskim |
| pubmed-article:7510257 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:7510257 | pubmed:dateCreated | 1994-4-8 | lld:pubmed |
| pubmed-article:7510257 | pubmed:abstractText | The conserved regulators of cell cycle progression--Cyclins, Cdc2 kinase, and String phosphatase (Cdc25)--accommodate multiple modes of regulation during Drosophila embryogenesis. During cell cycles 2-7, Cdc2/Cyclin complexes are continuously present and show little fluctuation in abundance, phosphomodification, or activity. This suggests that cycling of the mitotic apparatus does not require cytoplasmic oscillations of known regulatory activities. During cycles 8-13 a progressive increase in the degradation of Cyclins at mitosis leads to increasing oscillations of Cdc2 kinase activity. Mutants deficient in cyclin mRNAs suffer cell cycle delays during this period, suggesting that Cyclin accumulation times these cycles. During interphase 14, programmed degradation of maternal String protein leads to inhibitory phosphorylation of Cdc2 and cell cycle arrest. Subsequently, mitoses 14-16 are triggered by pulses of zygotic string transcription. | lld:pubmed |
| pubmed-article:7510257 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7510257 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7510257 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7510257 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7510257 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7510257 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7510257 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7510257 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7510257 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7510257 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7510257 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:7510257 | pubmed:issn | 0890-9369 | lld:pubmed |
| pubmed-article:7510257 | pubmed:author | pubmed-author:O'FarrellP... | lld:pubmed |
| pubmed-article:7510257 | pubmed:author | pubmed-author:LeopoldPP | lld:pubmed |
| pubmed-article:7510257 | pubmed:author | pubmed-author:SprengerFF | lld:pubmed |
| pubmed-article:7510257 | pubmed:author | pubmed-author:DuronioR JRJ | lld:pubmed |
| pubmed-article:7510257 | pubmed:author | pubmed-author:EdgarB ABA | lld:pubmed |
| pubmed-article:7510257 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7510257 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:7510257 | pubmed:volume | 8 | lld:pubmed |
| pubmed-article:7510257 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7510257 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7510257 | pubmed:pagination | 440-52 | lld:pubmed |
| pubmed-article:7510257 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:7510257 | pubmed:meshHeading | pubmed-meshheading:7510257-... | lld:pubmed |
| pubmed-article:7510257 | pubmed:meshHeading | pubmed-meshheading:7510257-... | lld:pubmed |
| pubmed-article:7510257 | pubmed:meshHeading | pubmed-meshheading:7510257-... | lld:pubmed |
| pubmed-article:7510257 | pubmed:meshHeading | pubmed-meshheading:7510257-... | lld:pubmed |
| pubmed-article:7510257 | pubmed:meshHeading | pubmed-meshheading:7510257-... | lld:pubmed |
| pubmed-article:7510257 | pubmed:meshHeading | pubmed-meshheading:7510257-... | lld:pubmed |
| pubmed-article:7510257 | pubmed:meshHeading | pubmed-meshheading:7510257-... | lld:pubmed |
| pubmed-article:7510257 | pubmed:meshHeading | pubmed-meshheading:7510257-... | lld:pubmed |
| pubmed-article:7510257 | pubmed:meshHeading | pubmed-meshheading:7510257-... | lld:pubmed |
| pubmed-article:7510257 | pubmed:meshHeading | pubmed-meshheading:7510257-... | lld:pubmed |
| pubmed-article:7510257 | pubmed:meshHeading | pubmed-meshheading:7510257-... | lld:pubmed |
| pubmed-article:7510257 | pubmed:meshHeading | pubmed-meshheading:7510257-... | lld:pubmed |
| pubmed-article:7510257 | pubmed:meshHeading | pubmed-meshheading:7510257-... | lld:pubmed |
| pubmed-article:7510257 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:7510257 | pubmed:articleTitle | Distinct molecular mechanism regulate cell cycle timing at successive stages of Drosophila embryogenesis. | lld:pubmed |
| pubmed-article:7510257 | pubmed:affiliation | Department of Biochemistry and Biophysics, University of California, San Francisco 94143. | lld:pubmed |
| pubmed-article:7510257 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7510257 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:7510257 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:34411 | entrezgene:pubmed | pubmed-article:7510257 | lld:entrezgene |
| entrez-gene:37618 | entrezgene:pubmed | pubmed-article:7510257 | lld:entrezgene |
| entrez-gene:39340 | entrezgene:pubmed | pubmed-article:7510257 | lld:entrezgene |
| entrez-gene:43466 | entrezgene:pubmed | pubmed-article:7510257 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7510257 | lld:pubmed |
