Linked Life Data

7509059

Source:http://linkedlifedata.com/resource/pubmed/id/7509059

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1994-3-21
pubmed:abstractText
There is no single characteristic or marker that identifies a dendritic cell. This review of the methods used for dendritic cell identification stresses that changes occur over the lifetime and changing functional status of the cell. Human dendritic cell populations have been obtained from adult peripheral blood, umbilical cord blood, bone marrow, thymus, and monocytes as starting substrates. Most recently dendritic cell populations have been grown from separated hematopoietic precursors, suggesting that there is a common granulocyte-monocyte-dendritic cell progenitor. Whether monocytes and dendritic cells can be modulated back and forth remains an open question. Granulocyte-monocyte colony stimulating factor (GM-CSF) appears to be critical to the development and function of these enriched and cultured cells. The characteristics of the cells produced by these various methods are tabulated. Important to the understanding of Langerhans cell biology is the variation in CD1 expression under different circumstances.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0277-0938
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
821-37
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Review of human dendritic cells: isolation and culture from precursors.
pubmed:affiliation
Department of Pathology, Children's Hospital of Pittsburgh, Pennsylvania 15213.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't