rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1994-3-18
|
pubmed:abstractText |
Patients with unstable angina despite intensive medical therapy, ie, refractory angina, are at high risk for developing thrombotic complications: myocardial infarction or coronary occlusion during percutaneous transluminal coronary angioplasty (PTCA). Chimeric 7E3 (c7E3) Fab is an antibody fragment that blocks the platelet glycoprotein (GP) IIb/IIIa receptor and potently inhibits platelet aggregation.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0009-7322
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
89
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
N
|
pubmed:pagination |
596-603
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:7508826-Adult,
pubmed-meshheading:7508826-Aged,
pubmed-meshheading:7508826-Angina, Unstable,
pubmed-meshheading:7508826-Angioplasty, Balloon, Coronary,
pubmed-meshheading:7508826-Antibodies, Monoclonal,
pubmed-meshheading:7508826-Bleeding Time,
pubmed-meshheading:7508826-Coronary Angiography,
pubmed-meshheading:7508826-Female,
pubmed-meshheading:7508826-Humans,
pubmed-meshheading:7508826-Immunoglobulin Fab Fragments,
pubmed-meshheading:7508826-Integrins,
pubmed-meshheading:7508826-Male,
pubmed-meshheading:7508826-Middle Aged,
pubmed-meshheading:7508826-Myocardial Ischemia,
pubmed-meshheading:7508826-Platelet Function Tests,
pubmed-meshheading:7508826-Platelet Glycoprotein GPIIb-IIIa Complex,
pubmed-meshheading:7508826-Postoperative Complications,
pubmed-meshheading:7508826-Treatment Outcome
|
pubmed:year |
1994
|
pubmed:articleTitle |
Randomized trial of a GPIIb/IIIa platelet receptor blocker in refractory unstable angina. European Cooperative Study Group.
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pubmed:affiliation |
Thoraxcenter, Rotterdam, The Netherlands.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|