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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1994-3-4
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pubmed:abstractText |
Neointimal hyperplasia is a leading cause of restenosis after vascular procedures. Recent findings showed that smooth muscle cell (SMC) migration from the media into the neointima is a critical step in the development of the hemodynamically compromising neointimal lesion. Moreover, integrins are believed to play a role in SMC motility. Therefore we studied the role of one ubiquitous integrin, alpha V beta 3, in SMC migration.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0741-5214
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
125-34
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7508000-Amino Acid Sequence,
pubmed-meshheading:7508000-Animals,
pubmed-meshheading:7508000-Antibodies, Monoclonal,
pubmed-meshheading:7508000-Cell Movement,
pubmed-meshheading:7508000-Cells, Cultured,
pubmed-meshheading:7508000-Humans,
pubmed-meshheading:7508000-Hyperplasia,
pubmed-meshheading:7508000-Integrins,
pubmed-meshheading:7508000-Male,
pubmed-meshheading:7508000-Molecular Sequence Data,
pubmed-meshheading:7508000-Muscle, Smooth, Vascular,
pubmed-meshheading:7508000-Oligopeptides,
pubmed-meshheading:7508000-Platelet Membrane Glycoproteins,
pubmed-meshheading:7508000-Rabbits,
pubmed-meshheading:7508000-Receptors, Cytoadhesin,
pubmed-meshheading:7508000-Receptors, Vitronectin,
pubmed-meshheading:7508000-Tunica Intima
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pubmed:year |
1994
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pubmed:articleTitle |
Inhibition of neointimal hyperplasia by blocking alpha V beta 3 integrin with a small peptide antagonist GpenGRGDSPCA.
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pubmed:affiliation |
Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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