Linked Life Data

7505865

Source:http://linkedlifedata.com/resource/pubmed/id/7505865

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1994-1-31
pubmed:abstractText
The fluorescent retrograde tracers Rhodamine B Isothiocyanate (RITC) and Fast Blue (FB) were injected either into the thalamic nucleus rotundus or into the complexus neck muscle in pigeons. Both in the rotundal and the peripheral motor preparations RITC yielded a 3-5 times larger number of afferent ipsilateral neurones than FB. While RITC additionally labelled a large number of contralateral afferents, virtually no labelled cells were detected contralateral to the injection site using FB. This selective omission of the contralateral input with FB was identical for both neural systems despite differences in injection volume, survival time, and transport length. In the present case, this structure-specific sensitivity of FB would lead to the erroneous conclusion that contralateral afferents are virtually non-existent in the visual tectofugal and the peripheral motor system. Thus, these results make it likely that the choice for a certain tracer may lead to different connectional interpretations of a neural system. Although the mechanism for these structure-specific sensitivity differences are unknown, it is suggested that tracers with lower effectivity like FB may be unable to label afferent structures with fewer axon terminals.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0165-0270
pubmed:author
pubmed:issnType
Print
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
103-11
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Different sets of afferents are demonstrated by the fluorescent tracers fast blue and rhodamine.
pubmed:affiliation
AE Biopsychologie, Fakultät für Psychologie, Ruhr-Universität Bochum, Germany.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't