Linked Life Data

7503636

Source:http://linkedlifedata.com/resource/pubmed/id/7503636

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1996-1-17
pubmed:abstractText
Two anthracycline drugs--doxorubicin and 4'-epidoxorubicin--synthesized at the Institute of Biotechnology and Antibiotics were tested in vivo for their biological activity in comparison with original Farmitalia drugs. In parallel experiments similar properties of both drugs and referentials were displayed: comparable subacute and delayed toxicity from i.p. and i.v. routes of administration as well as antitumor effectiveness in two mouse transplantable tumor models--P388 leukemia and B16 melanoma. No statistically significant differences between reproduced and original drugs were found.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0004-069X
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
51-62
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Comparative evaluation of toxicity and antitumor activity of original and reproduced anthracycline drugs.
pubmed:affiliation
Department of Tumor Immunology, Polish Academy of Sciences, Wroc?aw.
pubmed:publicationType
Journal Article, Comparative Study