Linked Life Data

7502071

Source:http://linkedlifedata.com/resource/pubmed/id/7502071

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5242
pubmed:dateCreated
1996-1-18
pubmed:abstractText
Embryonic development in mammals is distinct from that in other vertebrates because it depends on a small number of imprinted genes that are specially expressed from either the maternal or paternal genome. Why mammals are uniquely dependent on sexual reproduction and how this dependency is dictated at a molecular level are questions that have been intensively investigated during the past 2 years. Gene inactivation experiments have confirmed predictions that imprinted genes regulate embryonic and placental growth and that DNA methylation is part of the imprinting mechanism. Despite these considerable achievements, the reason why imprinted hemizygosity is used as a mechanism to regulate the intrauterine growth of mammalian embryos remains elusive.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0036-8075
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
270
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1610-3
pubmed:dateRevised
2007-3-19
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Gametic imprinting in mammals.
pubmed:affiliation
Institute of Molecular Pathology, Vienna, Austria.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't