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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1996-1-18
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pubmed:abstractText |
Microsatellite instability is a property of most tumors occurring in the context of hereditary nonpolyposis colon cancer. Instability also occurs in 10%-15% of apparently sporadic colorectal cancers, and it has been hypothesized that this instability may indicate a genetic predisposition to colonic cancer. This study evaluated whether there is a clinically useful association between colon cancer instability and a family history of cancer.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
109
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1765-71
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7498640-Adult,
pubmed-meshheading:7498640-Aged,
pubmed-meshheading:7498640-Base Sequence,
pubmed-meshheading:7498640-Case-Control Studies,
pubmed-meshheading:7498640-Chi-Square Distribution,
pubmed-meshheading:7498640-Colonic Neoplasms,
pubmed-meshheading:7498640-Colorectal Neoplasms,
pubmed-meshheading:7498640-Family Health,
pubmed-meshheading:7498640-Female,
pubmed-meshheading:7498640-Genotype,
pubmed-meshheading:7498640-Glutathione Transferase,
pubmed-meshheading:7498640-Humans,
pubmed-meshheading:7498640-Male,
pubmed-meshheading:7498640-Microsatellite Repeats,
pubmed-meshheading:7498640-Middle Aged,
pubmed-meshheading:7498640-Molecular Sequence Data,
pubmed-meshheading:7498640-Polymerase Chain Reaction,
pubmed-meshheading:7498640-Predictive Value of Tests
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pubmed:year |
1995
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pubmed:articleTitle |
Microsatellite instability in human colonic cancer is not a useful clinical indicator of familial colorectal cancer.
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pubmed:affiliation |
Department of Pathology, University of Utah School of Medicine, Salt Lake City, USA.
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pubmed:publicationType |
Journal Article,
Comment,
Research Support, U.S. Gov't, P.H.S.
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