| pubmed-article:7497591 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7497591 | lifeskim:mentions | umls-concept:C0043343 | lld:lifeskim |
| pubmed-article:7497591 | lifeskim:mentions | umls-concept:C1335132 | lld:lifeskim |
| pubmed-article:7497591 | lifeskim:mentions | umls-concept:C0022646 | lld:lifeskim |
| pubmed-article:7497591 | lifeskim:mentions | umls-concept:C0242643 | lld:lifeskim |
| pubmed-article:7497591 | lifeskim:mentions | umls-concept:C0029045 | lld:lifeskim |
| pubmed-article:7497591 | lifeskim:mentions | umls-concept:C0205245 | lld:lifeskim |
| pubmed-article:7497591 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:7497591 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:7497591 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:7497591 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:7497591 | pubmed:dateCreated | 1996-1-17 | lld:pubmed |
| pubmed-article:7497591 | pubmed:abstractText | The hypothesis that P-glycoprotein (P-gp) mediates the renal secretion of organic cations was tested by functional expression of mRNAs in the Xenopus laevis oocyte system. Efflux of 2'-deoxytubercidin (dTub), a substrate for the renal organic cation transporter (OCT) but not for P-gp, was enhanced by injection of renal mRNA but not by injection of mRNA from P-gp-overexpressing cells (MDCK cells transduced with the cDNA for human MDR1). The functional capacity of the MDCK-MDR mRNA was established by its ability to reduce the steady-state uptake of a classical P-gp substrate, vinblastine. Thus, these data indicate OCT and P-gp to be distinct entities. The Xenopus oocyte system provides a functional approach to further characterize the OCT. | lld:pubmed |
| pubmed-article:7497591 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7497591 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7497591 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7497591 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7497591 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7497591 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7497591 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7497591 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7497591 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7497591 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7497591 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7497591 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7497591 | pubmed:issn | 0344-5704 | lld:pubmed |
| pubmed-article:7497591 | pubmed:author | pubmed-author:NelsonJ AJA | lld:pubmed |
| pubmed-article:7497591 | pubmed:author | pubmed-author:WrightD ADA | lld:pubmed |
| pubmed-article:7497591 | pubmed:author | pubmed-author:DuttAA | lld:pubmed |
| pubmed-article:7497591 | pubmed:author | pubmed-author:AllenL HLH | lld:pubmed |
| pubmed-article:7497591 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7497591 | pubmed:volume | 37 | lld:pubmed |
| pubmed-article:7497591 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7497591 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7497591 | pubmed:pagination | 187-9 | lld:pubmed |
| pubmed-article:7497591 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:7497591 | pubmed:meshHeading | pubmed-meshheading:7497591-... | lld:pubmed |
| pubmed-article:7497591 | pubmed:meshHeading | pubmed-meshheading:7497591-... | lld:pubmed |
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| pubmed-article:7497591 | pubmed:meshHeading | pubmed-meshheading:7497591-... | lld:pubmed |
| pubmed-article:7497591 | pubmed:meshHeading | pubmed-meshheading:7497591-... | lld:pubmed |
| pubmed-article:7497591 | pubmed:meshHeading | pubmed-meshheading:7497591-... | lld:pubmed |
| pubmed-article:7497591 | pubmed:meshHeading | pubmed-meshheading:7497591-... | lld:pubmed |
| pubmed-article:7497591 | pubmed:meshHeading | pubmed-meshheading:7497591-... | lld:pubmed |
| pubmed-article:7497591 | pubmed:meshHeading | pubmed-meshheading:7497591-... | lld:pubmed |
| pubmed-article:7497591 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7497591 | pubmed:articleTitle | Functional expression of the renal organic cation transporter and P-glycoprotein in Xenopus laevis oocytes. | lld:pubmed |
| pubmed-article:7497591 | pubmed:affiliation | Department of Experimental Pediatrics, University of Texas M.D. Anderson Cancer Center, Houston 77030, USA. | lld:pubmed |
| pubmed-article:7497591 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7497591 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
