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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1996-1-16
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pubmed:abstractText |
The effect of weight loss on immuno function was evaluated in 14 middle-aged obese women. Cutaneous delayed-type hypersensitivity to five recall antigens was measured before a weight loss of 21 kg and again after weight had been stabilized. Weight loss was associated with a decrease in both number and magnitude of delayed-type hypersensitivity responses. The number of positive skin tests decreased from 3.1 +/- 0.2 to 2.4 +/- 0.3 per subject, and the mean cutaneous induration size decreased by 38%. The decrease in induration size was positively correlated with the decrease in body mass index (r = 0.63), weight (r = 0.59), and fat mass (r = 0.52). These preliminary findings suggest that large weight losses may result in decreased expression of immune function.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-1083964,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-1277306,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-14062375,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-142452,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-1550063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-1902345,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-1962587,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-2058573,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-2186751,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-2643001,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-2666113,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-3326822,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-3871252,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-3942498,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-3971221,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-4107899,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-458167,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-4947653,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-5046466,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-538705,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-5643759,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-5786976,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-6859089,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-6965559,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-6993072,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-6995542,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-7098466,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-7353413,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-7368908,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-7466576,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-803774,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-810018,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496946-832199
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1071-412X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
202-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:7496946-Adult,
pubmed-meshheading:7496946-Body Composition,
pubmed-meshheading:7496946-Female,
pubmed-meshheading:7496946-Follow-Up Studies,
pubmed-meshheading:7496946-Humans,
pubmed-meshheading:7496946-Hypersensitivity, Delayed,
pubmed-meshheading:7496946-Immunity, Cellular,
pubmed-meshheading:7496946-Middle Aged,
pubmed-meshheading:7496946-Obesity,
pubmed-meshheading:7496946-Skin Tests,
pubmed-meshheading:7496946-Weight Loss
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pubmed:year |
1994
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pubmed:articleTitle |
Decline in delayed-type hypersensitivity response in obese women following weight reduction.
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pubmed:affiliation |
Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia 19104, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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