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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1996-1-18
|
| pubmed:abstractText |
Aberrations of the long arm of chromosome 5 (5q) were studied in 79 clear cell renal carcinomas (clear cell RCC) by LOH (loss of heterozygosity) method, using microsatellite markers D5S107, CRTL1, LNS-CA, IL-9.RP1, CFS1R and GeneScan analysis software. Alterations of chromosome 5q were detected in 42% of cases. We found, that accumulation of genomic abnormalities at multiple loci of 5q, especially in 5q21-qter region, where genes for cytokines are located, correlates with morphologic features of better prognosis.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1233-9687
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
46
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
163-6
|
| pubmed:dateRevised |
2007-8-1
|
| pubmed:meshHeading |
pubmed-meshheading:7496735-Adenocarcinoma, Clear Cell,
pubmed-meshheading:7496735-Base Sequence,
pubmed-meshheading:7496735-Chromosome Aberrations,
pubmed-meshheading:7496735-Chromosomes, Human, Pair 5,
pubmed-meshheading:7496735-Cytokines,
pubmed-meshheading:7496735-DNA, Neoplasm,
pubmed-meshheading:7496735-Genetic Markers,
pubmed-meshheading:7496735-Humans,
pubmed-meshheading:7496735-Kidney Neoplasms,
pubmed-meshheading:7496735-Molecular Sequence Data,
pubmed-meshheading:7496735-Polymerase Chain Reaction,
pubmed-meshheading:7496735-Prognosis
|
| pubmed:year |
1995
|
| pubmed:articleTitle |
Abnormalities of chromosome 5q correlate with morphologic features of better prognosis in clear cell renal carcinomas.
|
| pubmed:affiliation |
Department of Genetics and Pathology, Medical Academy, Szczecin.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|