Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1979-6-11
pubmed:abstractText
Knowledge of the course of active and passive pressure regulation of the heart is essential for characterizing its faculty of self-regulation. We therefore studied the adjustment of systolic and end-diastolic pressure development through the left ventricle of the heart-lung preparation of rat against an acutely enhanced outflow resistance. It had been determined previously, how and how long hemodynamic stability of the preparation could be reached and maintained under the given experimental conditions. On sudden enhancement of the outflow resistance from 60 to values of 100--160 mm Hg we observed a multiphasic response of the systolic and diastolic pressure whose extent and dynamics were proportional to load. The ability of the end-diastolic pressure to re-adjust was determined to be 60--68%. The results suggest a multifactorial mechanism of self-regulation.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0001-5318
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1479-87
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
[Adjustment of systolic and diastolic pressure in the left ventricle during acute changes in outflow resistance in a rat heart-lung preparation].
pubmed:publicationType
Journal Article, English Abstract