Linked Life Data

7493459

Source:http://linkedlifedata.com/resource/pubmed/id/7493459

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1996-1-11
pubmed:abstractText
Ornamental cultivars of Tagetes sp., commonly named marigold, are one of the presently most popular pot and garden plants. Sensitizing experiments in guinea pigs with short ether extracts and isolated compounds revealed the presence of 3 constituents that must be considered as contact allergens. They were identified as 5-(3-buten-1-ynyl)-2,2'-bithiophene, alpha-terthienyl and hydroxytremetone. In sensitized animals, butenylbithiophene showed moderate to strong sensitizing potency, while alpha-terthienyl was less strong and hydroxytremetone weak. The results demonstrate, for the first time, that at least some of the thiophenes abundantly occurring in many species of the Compositae family possess not only phototoxic activity but also sensitizing properties.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0105-1873
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
33-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Butenylbithiophene, alpha-terthienyl and hydroxytremetone as contact allergens in cultivars of marigold (Tagetes sp.).
pubmed:affiliation
Department of Dermatology, University Hospital Hamburg, Germany.
pubmed:publicationType
Journal Article