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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1996-1-4
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pubmed:abstractText |
Lymphocytic gastritis and primary gastric lymphoma are rare conditions with unknown aetiology. It has recently been suggested that Helicobacter pylori has a role in the pathogenesis of both of them. The occurrence of lymphocytic gastritis and H pylori was studied in a series of patients with primary gastric lymphoma. The cases of primary gastric lymphomas (n = 35) diagnosed in years 1970-1993 were identified. The specimens of 22 cases contained gastric mucosa sufficiently so that the number of intra-epithelial lymphocytes, severity of gastritis, and occurrence of H pylori could be studied. Lymphocytic gastritis was detected in seven of 22 patients (32%), and in most cases both in antral and body mucosa. Atrophy of the body glands was significantly more severe in lymphocytic gastritis patients. H pylori was detected in 13 of all 22 patients (59%); two of seven lymphocytic gastritis patients (29%), and 11 of 15 (73%) of patients without lymphocytic gastritis were H pylori positive. Patients with gastric lymphoma have significantly increased prevalence of lymphocytic gastritis. Rarity of H pylori in these patients might be connected with atrophic changes in body mucosa. Further studies are needed to show the significance of lymphocytic gastritis as a precursor of gastric lymphoma.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/7489930-1347858,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/7489930-8707131
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0017-5749
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
471-6
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:7489930-Adult,
pubmed-meshheading:7489930-Aged,
pubmed-meshheading:7489930-Aged, 80 and over,
pubmed-meshheading:7489930-Female,
pubmed-meshheading:7489930-Gastric Mucosa,
pubmed-meshheading:7489930-Gastritis,
pubmed-meshheading:7489930-Helicobacter Infections,
pubmed-meshheading:7489930-Helicobacter pylori,
pubmed-meshheading:7489930-Humans,
pubmed-meshheading:7489930-Lymphocyte Count,
pubmed-meshheading:7489930-Lymphocytosis,
pubmed-meshheading:7489930-Lymphoma, B-Cell,
pubmed-meshheading:7489930-Male,
pubmed-meshheading:7489930-Middle Aged,
pubmed-meshheading:7489930-Stomach Neoplasms
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pubmed:year |
1995
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pubmed:articleTitle |
Lymphocytic gastritis and Helicobacter pylori infection in gastric lymphoma.
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pubmed:affiliation |
Department of Pathology, University of Oulu, Finland.
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pubmed:publicationType |
Journal Article
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