rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1995-11-30
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pubmed:abstractText |
In a large public urban hospital obstetrics service with > 123,000 deliveries in a 10-year period (1980-89), the frequencies (0.12%) of any type of chromosomal abnormality and of trisomy syndromes were analyzed for maternal age-related risk, by logistic regression. Focusing on very young gravidas, we found that in the study period there were 9,332 births (7.5% of all deliveries) to mothers < or = 16 years old. Estimated risks of chromosomal abnormalities among offspring associated with very young maternal age (9-16 years) were similar to those age-associated risks of mothers 20-29 years old. Risks of chromosomal abnormalities increase with advancing maternal age and are independent of ethnicity.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0002-9297
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1178-85
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:7485170-Adolescent,
pubmed-meshheading:7485170-Adult,
pubmed-meshheading:7485170-Amniocentesis,
pubmed-meshheading:7485170-Child,
pubmed-meshheading:7485170-Chromosome Aberrations,
pubmed-meshheading:7485170-Chromosomes, Human, Pair 13,
pubmed-meshheading:7485170-Chromosomes, Human, Pair 18,
pubmed-meshheading:7485170-Down Syndrome,
pubmed-meshheading:7485170-Humans,
pubmed-meshheading:7485170-Karyotyping,
pubmed-meshheading:7485170-Maternal Age,
pubmed-meshheading:7485170-Middle Aged,
pubmed-meshheading:7485170-Mothers,
pubmed-meshheading:7485170-Risk Factors
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pubmed:year |
1995
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pubmed:articleTitle |
Risk of chromosomal abnormalities, with emphasis on live-born offspring of young mothers.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas 75235-9032, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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