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pubmed-article:7485096pubmed:abstractTextClonal disorders of large granular lymphocytes (LGL) of either CD3- (NK cell) or CD 3+ (T-cell) phenotype have been described. B-cell malignancies such as hairy cell leukemia and non-Hodgkin's lymphoma have been observed in association with the T-cell type of LGL leukemia. Here we report the occurrence of LGL lymphocytosis in four patients with Hodgkin's disease. Immunophenotyping studies showed that these LGL were CD 3- in three patients and CD3+ in the other. LGL were polyclonally expanded in both patients in whom clonality could be assessed.lld:pubmed
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pubmed-article:7485096pubmed:articleTitleLymphocytosis of large granular lymphocytes in patients with Hodgkin's disease.lld:pubmed
pubmed-article:7485096pubmed:affiliationVeteran's Administration Hospital, Syracuse, NY 13210, USA.lld:pubmed
pubmed-article:7485096pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:7485096pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed